邢唷> 13./0欹 餜xKbjbj2s2s8PP BB8d;C#(O>z"|"|"|"|"|"|"$%'L"]OO"H"z"z"v怱;鐸f"#0C#, (( (($""C#(B Q: 藛}v(Nv戝] z zYef['Y瞺 Course Outline z鶺,g酧o`Course Information  z鉔x Course Code BIO3206*f[鰁 Credit Hours 32*f[R Credits 2* z T饄 Course Title -N噀 藛}v(Nv戝] z駛噀 Protein and Enzyme Engineering* z'`( Course Type 臺頞 Compulsory courses坈鵞a Target Audience uir錧 z0uirb/gNN,g褃u*坈韹 (Language of Instruction)-N噀*_b桘| School u}T褃f[b/gf[bHQ頞 z Prerequisite  0uirSf[ 00 0 g:gSf[ 00 0甠uirf[ 00 0RP[W Of[ 0 Biochemistry, Organic chemistry, Microbiology, Molecular genetics坈Ye^ Instructor 1u穇梘 zQ@W (Course Webpage)ftp://public.sjtu.edu.cn/* z{薔Description  0藛}v(Nv戝] z 0/fN钑藛}v(Sf[0v慺[孴錧 zf[鴙觺T剉 z ,g z剉;N亯顅剉/ft銐v戝] z祄講剉匭筟0宑醕v戝] z剉鶺,gt簨 v懍PS蚐擽剉鶺@x鍂茓0焣塦v(u嶯u g(uir(岪b梺墑v鼅T'`剉 鑽f[褃剉筫誰0哊銐藛}v(Nv戝] z鴙sQ癳蹚U\孴xQ媁瀃婳 觔U\鵞uir錧 z鴙sQ啒遅剉`魚齹汻孴鼅T茐螒0* z{薔Description The purpose of the course is to give biological engineering undergraduates an understanding and an overview of the subject of enzyme engineering. The fundamentals of enzyme-catalyzed reactions will be introduced, especially as they apply to large scale production of small molecules. This course aims to familiarize participants with the integrated, interdisciplinary approach required to utilize the catalytic potential of enzymes for the production of useful compounds. zYef['Y瞺course syllabus *f[`N顅h(Learning Outcomes)(1) 宑醕v戝] z剉俰鮛0顅剉0皊秗孴cb0 (2) 焣塦v憯^(u嶯uir琍S剉O筽孴P6R郪 }0 (3) 宑醕'Y膲!j錧N擽(u剉v懍PS蚐擽0 (4) 宑醕蛻膥v憚v[{ 0KQ問0h埦弻T裇u0 (5) 焣塦O(u瘇繯v憣ThQ苸迉(u嶯uir琍S剉頬_0 (6) t銐v憯^(u嶯邩罷錧N0淨N孴~rSf[罷錧N剉uir菑 z0 (7) 齹裇榗錧 zS筫Hh 銐砆v(u嶯uir琍S剉P6R郪 }0 (8) 齹vzuirf[筫誰 銐砆v(u嶯uir琍S剉P6R郪 }0 (1) Understanding purpose, status, perspective, and challenges of enzyme engineering. (2)  HYPERLINK "http://www.jukuu.com/show-familiarizing-0.html" Familiarizing the advantages and limitations of using enzymes for biocatalysts. (3) To learn biocatalytic reactions on an industrial scale catalyzed by useful enzyme. (4)  HYPERLINK "http://www.jukuu.com/show-familiarizing-0.html" Familiarizing cloning and expression of recombinant enzymes. (5)To understand differences between using purified enzymes and whole cell as the biocatalysts. (6) Understanding biological processes of using enzymes for the food industry, agriculture and green chemicals. (7) Finding engineering solutions to these limitations of using enzymes for biocatalysts. (8) Exploring biological solutions to these limitations of using enzymes for biocatalysts.*8:nrz~    蜴諮藕搏搳}湂s妌渳渇_X}Ph鮣rh礮o( h鮣rh*& h<h:h<h<o( h<o(h鮣rh:RHZo(h鮣rh0B*o(phh鮣rh:RHZh<h<RHZ h鮣rh:h鮣rh:o( h鮣rh h鮣rh o(h礮h礮CJ aJ h礮h礮CJ aJ o(h 5丆J aJ h h 5丆J aJ h礮h 5丆J aJ h<h<5丆J aJ o(:pr|qee\eee $Ifgd) $$Ifa$gd鮣rykd$$If杔攆;#&  t 儋0&644 lap 儋yt鮣r $$Ifa$gd鮣r$a$gd礮  $$Ifa$gd< $$Ifa$gd鮣rkd$$If杔/謭; }BY#f  t0&644 lap<yt鮣r 8 : < `TK $Ifgd< $$Ifa$gd鮣rkd$$If杔4斃0;#f ^ t0&644 lapyt鮣r $Ifgd礮 $$Ifa$gd鮣r ( 6 < D \   & * , 4 6 h j n r t | ~ 妁褓軒沒懷鶓姂硞憡か娒基基z鵰基基h鮣rh0B*o(phhh<o(h鮣rh畗o( h鮣rhilh鮣rhilo(h鮣rh B* ph癙 h,h<h,h<o(h鮣rh礮o(h鮣rh o(h鮣rh礮B*o(phh<CJQJo(h<h<CJQJo(h<h<CJaJo(h鮣rhCiho( h鮣rh ) uii]] $$Ifa$gd< $$Ifa$gd鮣rkd$$If杔4敍0;# f ^ t0&644 lapyt鮣r ( vjj^ $$Ifa$gd鮣r $$Ifa$gd鮣rkdf$$If杔敿0;#f ^ t0&644 lapyt鮣r( * 6 j p xl`` $$Ifa$gd鮣r $$Ifa$gd鮣rkd$$If杔0;#f ^ t0&644 lapyt鮣rp r ~ xll` $$Ifa$gd< $$Ifa$gd鮣rkd$$If杔0;#f ^ t0&644 lapyt鮣r   " @ D ` d     $ > @ J X 塍塍爿爿爿爿箅箅噪篾筇盤盤盤缶釩霊髞qh9-&h<OJQJ^JaJo(h<h<OJQJ^JaJo(h鮣rh RHZo(h鮣rh4z"o(h鮣rhaTVB*o(ph h鮣rh*& h<h  h<h< h鮣rhCihh鮣rhCiho(h鮣rh畗o( h,h<h,h<o(h鮣rh o( h鮣rh  h<o()  xll`` $$Ifa$gd< $$Ifa$gd鮣rkd$$If杔0;#f ^ t0&644 lapyt鮣r  xllllll $$Ifa$gd鮣rkd>$$If杔0;#f ^ t0&644 lapyt鮣r  @ ^ F:1 $Ifgd< $$Ifa$gd鮣rkd$$If杔謀;}#f  /I t0&6 44 lap(yt鮣rX d ~   . 6 < > H R V Z \ ` b j 蜮肘蜮燭餷餷蛑蛑蛑蛑嗆球猹蜮洈u攏gn h9-&h< hB"h<h鮣rh RHZo(h鮣rh o(h鮣rhaTVB*o(ph h鮣rh h藋h<OJQJ^JaJh藋h<OJQJ^JaJo(h18OJQJ^JaJo(h9-&h<OJQJ^JaJh<OJQJ^JaJh9-&h<OJQJ^JaJo(h<OJQJ^JaJo('^ ` vja $Ifgd< $$Ifa$gd鮣rkd$$If杔斃0;#f ^ t0&644 lapyt鮣r ASTUV,.24bd"JPRTZ\|熹燧先攔攔葴棎湕湕湕湕湕湕湕湕湕湕 hdBh18 h18o(hdBh18o(h鮣rh o(h鮣rhtB* o(ph h鮣rh廡 h鮣rh廡 o( h鮣rh  h<h  hr&Rh< hSh<hPh<o( hB"h< h"Ih< h<o(50vm $IfgdCihkd$$If杔攁0;#f ^ t0&644 lapyt鮣r02dNWymmmmmmmmd $Ifgd18 $$Ifa$gd18 $$Ifa$gd鮣rykdm $$If杔-;#&  t 儋0&644 lap 儋yt鮣r CUVWXYZ[\蜴蜴蜴蜴蜣俎袞騮騮孓咽偈傺倨舉堆傺潳贊伽贂幨幤庂奄咽 h!h18h9Gh18o( hCnh18jhCnh18U h9Gh18h ;kh18o(hPh18o(h18 h/h18hcsuh18o( h18o(hdBh18o(h18OJQJ^JaJh18OJQJ^JaJo(7WA!FGD:Dm^^$d4$Ifa$gd鮣rkd $$If杔攬 0;#f ^ t0&644 lapyt鮣r $Ifgd18   $./2?ABCDEF  !"#$&/3GHQX\np"#,3BCDEF驃驃摁拮套挑佐替摁捩沛翩翩艮艮翩繇僚媾留留留摁摁沛帕鵬摁摁鵬沛帕鵬 h鮣rhCihh18 h!h18jhCnh18U hCnh18hcsuh18o( h/h18 h~HYh18 h18o( h蘒h18GFGDDDD:Dy, 2011 Principles of enzyme engineering. Beijing: science press, 2011. 耂fN顅 0uir琍S-鶺@xN擽(u 0Y[譥im0笅鷁孴褘,Sf[錧N鶴Hr>y, 2006 Biocatalysis: fundamentals and applications. Andreas S. Bommarius, Bettina R. 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