報告題目💊：Discovering New Enzymes for Biosynthesis and Biocatalysis

報  告 人🤽：唐奕 教授 （University of California Los Angeles)

報告時間：6月17日 上午9：00

報告地點：徐匯校區哲生館1樓會議室

聯  系 人🛌🏼：林雙君 This e-mail address is being protected from spambots. You need JavaScript enabled to view it.

報告摘要😛：

Biosynthesis of structurally complex natural products requires the coordinated actions of many enzymes.  Through the discovery and characterization of natural product biosynthetic pathways, many enzymes of novel structures and functions have been identified.  In this talk, I will discuss some interesting examples from our recent work on both bacterial and fungal secondary metabolism.  We will highlight studies on well-known (such as tetracycline and lovastatin) and newly discovered natural products.  In addition, I will also present protein engineering efforts in which a biosynthetic enzyme was converted into a commercial biocatalyst for the semisynthesis of a blockbuster drug.