報告題目👦🏼：Biological Processes for Conversion of Lignocellulosic Biomass to Fuels and Chemicals

報告人🍻：Venkatesh Balan博士

Department of Chemical Engineering and Material Science, Michigan State University

報告時間🪴：12月8日 14:00-15:00

報告地點🧑🏻‍⚕️：閔行校區生物藥學樓2號樓116會議室

聯系人🍥🥰：白鳳武 This e-mail address is being protected from spambots. You need JavaScript enabled to view it.

Abstract：Production of fuels and chemicals from lignocellulosic biomass (biorefinery) has gained much momentum due to its benefits to energy security, environmental and social sustainability. The current major issues impeding biochemical conversion of lignocellulosic biomass to fuels and chemicals include low yield at high solids loading, low productivity and high enzyme loading. High solids loadings (>18 wt%) during enzymatic hydrolysis and fermentation are desired for production of lignocellulosic biofuels and chemicals at a high titer, which lowers the processing cost. However, sugar conversion and product yield decrease with increasing solids loading. Moreover, the cost of enzymes for cellulose deconstruction is too high and is considered as one of the key bottlenecks for producing fuels and chemicals from lignocellulosic biomass, even though enzyme cost has been reduced by more than tenfold in the past 15 years. My talk will focus on production of ethanol and lipids from Ammonia Fiber Expansion (AFEXTM) pretreated and Extractive Ammonia (EA) pretreated biomass at high solids loading via a novel integrated enzymatic hydrolysis and microbial fermentation process. The process features several cost saving advantages that include (1) fast conversion of lignocellulosic biomass in hours rather than days (higher productivity), (2) about one third enzyme loading reduction through efficient enzyme recycling and (3) recycling of yeast cells during fermentation. Strategies adopted to overcome the bottlenecks during high solids loading process will be discussed in details.