On improving CRISPR gene editing technology 求真講壇第五期
發布時間 :2019-03-26  閱讀次數 :5245

講座時間⚅:2019-4-4 10:00-11:30

講座地點:閔行校區生物藥學樓樹華多功能廳

主 講 人:美國加州大學San Diego分校植物科學系系主任 教授

主辦單位🧎🏻:EON体育4平台

聯 系 人:邢海娜 (xinghaina@sjtu.edu.cn)

 

 

 

主講人簡介👩🏻‍🦰👂🏽:

   趙雲德,博士🥄,美國加州大學分校終身教授、南京農業大學講座教授👌🏽。1990年於中國科EON4上海藥物研究所獲微生物學碩士學位後赴美留學👴,在美國密歇根大學獲博士學位🤹🏽‍♀️,畢業後在著名的The Salk Institute進行博士後工作。主要從事生長素在發育過程中的作用機理方面的研究,在植物生長素的合成👩🏿‍🏫🦗、修飾、運輸和信號轉導的分子機理研究領域取得多項突破性成果♡。以第一作者或通訊作者身份在Science☮️、Cell📴、Gene and Development、PNAS👩🏽‍✈️、Plant Cell等國際著名期刊上發表多篇學術論文篇✏️,包括應邀為Annual Review of Plant Biology等雜誌所撰寫的綜述。文章引用數超過10000次, H指數51。

 

內容簡介:

CRISPR gene editing technologies have revolutionized biology and crop improvement. In this presentation, I will first describe the remaining challenges of gene editing technologies in plants followed by presenting our effort in improving several aspects of CRISPR gene editing technology. I will focus on two main areas of CRISPR technology: Homology-directed DNA repair (HDR) and transgene-free genome editing. HDR has been regarded as the Holy Grail of genome editing in plants and offers unprecedented applications in agriculture.  We have developed new strategies that enabled HDR-based gene replacements in plants. Transgene-free is likely a prerequisite to gain regulatory approval of edited crops. My group has pioneered several strategies that accelerate the isolation of transgene-free, gene-edited plants. Our latest technology allows the isolation of edited, transgene-free plants within a single generation, greatly accelerating crop breeding. I will use editing auxin pathways as an example to demonstrate the power of our new technologies in both basic and applied plant biology.

 

請感興趣的老師於2019年4月2日16:00之前報名。

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1.點擊以下網址

https://mp.weixin.qq.com/s/OmL3UfOQ9ELsTCgr327FyA

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