Geng Wu

Professor

  • Tel: +86-021-34205914
  • Email: geng.wu@sjtu.edu.cn
  • Address:
  • PhD, Princeton University, 2001. He published in Nature, Science, Mol Cell, Nat Catalysis, Nat Microbiol, Nat Commun as first/corresponding author and received the First Prize in Natural Science, Ministry of Education. His student was awarded Shanghai Excellent PhD thesis.

Selected Publications

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    Wu D, Tang Y, Chen S, He Y, Chang X, Zheng W, Deng Z, Li Z, Wang L*, Wu G*, Chen S*. The functional coupling between restriction and DNA phosphorothioation modification systems underlying the DndFGH restriction complex. Nature Catalysis Accepted.

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    Gao H, Gong X, Zhou J, Zhang Y, Duan J, Wei Y, Chen L, Deng Z, Wang J, Chen S*, Wu G*, Wang L*. Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE. Nature Communications 13(1):6773. (2022)

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    Ramlaul K, Fu W, Li H, Garrido NM, He L, Cui W, Aylett CHS*, Wu G*. Architecture of the Tuberous Sclerosis Protein Complex. Journal of Molecular Biology 433(2):166743. (2020,通訊作者,被選入Faculty Opinions生物醫藥類論文權威數據庫)

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    Xiong X#, Wu G#, Wei Y#, Liu L, Zhang Y, Su R, Jiang X, Li M, Gao H, Tian X, Zhang Y, Hu L, Chen S, Tang Y, Jiang S, Huang R, Li Z, Wang Y, Deng Z, Wang J, Dedon PC, Chen S, Wang L. SspABCD-SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities. Nature Microbiology 5(7):917-928(2020,第一作者)

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    Liu G, Fu W, Zhang Z, He Y, Yu H, Wang Y, Wang X, Zhao YL, Deng Z, Wu G*, He X*. Structural basis for the recognition of sulfur in phosphorothioated DNA. Nature Communications 9(1):4689.(2018,通訊作者)

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    Kulaberoglu Y#, Lin K#, Holder M, Gai Z, Gomez M, Shifa BA, Mavis M, Hua L, Sharif AAD, Lujan C, Smith EJ, Bjedov I, Tapon N, Wu G*, Hergovich A*. Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control. Nature Communications 8:695.(2017,通訊作者)

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    Mu Z, Wang L, Deng W, Wang J, Wu G*. Structural insight into the Ragulator complex which anchors mTORC1 to the lysosomal membrane. Cell Discovery 3:17049.(2017,通訊作者)

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    Gai Z, Wang Q, Yang C, Wang L, Deng W, Wu G*. Structural mechanism for the arginine sensing and regulation of CASTOR1 in the mTORC1 signaling pathway. Cell Discovery 2:16051.(2016)

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    Zhang Z, Chen L, Gao L, Lin K*, Zhu L, Lu Y, Shi X, Gao Y, Zhou J, Xu P, Zhang J*, Wu G*. Structural basis for the recognition of Asef by Adenomatous Polyposis Coli. Cell Research 22:372-386.(2012,通訊作者,被英國皇家學會院士Marian Bienz選入Faculty of 1000生物醫藥類論文權威數據庫)

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    Zhang Y, Fu L, Qi X, Zhang Z, Xia Y, Jia J, Jiang J, Zhao Y*, Wu G*. Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci. Nature Communications 4:2608.(2013,通訊作者)

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